This product is mouse monoclonal antibody recognizes SATB1 of human. The antibody 1D8 immunoassay techniques such as: IP, MA. Through a unique nuclear architecture, this gene encodes a matrix protein which binds nuclear matrix and scaffold-associating DNAs. The protein convenes chromatin-remodeling factors to regulate chromatin structure and gene expression. The key silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma (By similarity). This protein is thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. https://www.antibody-creativebiolabs.com/anti-satb1-antibody-1d8-677.htm